Wolbachia Mosquito Rearing Facilities

Reducing the spread of mosquito-borne diseases around the world

World Mosquito Program (WMP) | Brazil & Colombia | 2022-Ongoing

Dengue is the world's most rapidly spreading mosquito-borne disease with +50% of the world’s population at risk of infection.

Each year, an estimated 390 million dengue infections occur around the world, resulting in up to 36,000 deaths.

Wolbachia bacteria reduces dengue hospitalizations by 86%.

This method of Wolbachia mosquito rearing has been successfully deployed in 11 countries within the past decade.

Challenges

  • The World Mosquito Program (WMP), in an effort to reduce the transmission of mosquito-borne diseases worldwide, sought to develop global mass mosquito production facilities and mobile labs.
  • WMP needed a partner to support facility design and overall project management to develop production plants and facilities across the globe while navigating complex arrangements involving multiple regions, funding mechanisms, government bodies, commercial business, engineering standards, development approvals.

Solutions

  • Assisted WMP in designing facilities for the mass rearing of Wolbachia, a symbiotic bacterium able to block the transmission of viruses when introduced to disease-carrying mosquito species. This method effectively "immunizes" mosquito populations against dengue and other viruses.
  • Secured work for the program by leveraging our success in large-scale industrial and government agency projects, as well as our existing operations in several key regions including Brazil, Colombia, Australia, India, and Indonesia.
  • Our Australian team is coordinating the design and site selection across Brazil and Colombia for multiple facilities, using our global expertise to navigate region-specific standards and procurement strategies.
  • Helped WMP coordinate the development and installation of HVAC, energy, lighting, telecommunications, water, potable and wastewater treatment, and containment and quarantine infrastructure.

Highlights

  • Using Wolbachia to immunize disease-carrying mosquito species has been successfully implemented as a self-sustaining, cost-effective method in 11 countries over the past decade, reaching over 10 million people.
  • Wolbachia, which occurs naturally in half of all insect species, has proven effective against all four dengue virus stereotypes, with similar deployment programs reducing dengue incidents by 77% and hospitalizations by 86%.
  • When completed, the Brazil facility will be equipped with two mosquito lines and clear separation between manufacturing spaces for mosquito strains from different regions or cities, able to produce 5 million mosquitoes a week.

“The movement of people from rural areas to cities, climate change, and international travel have all contributed to the increased global spread of viruses transmitted by the Aedes aegypti mosquito – including dengue, Zika, yellow fever, and chikungunya. Dengue is the world’s most rapidly spreading mosquito-borne disease, currently affecting more than half the world’s population and that number is projected to increase substantially over the next 50 years." “Working in conjunction with Hatch’s teams of highly skilled engineers will allow the World Mosquito Program to work closely with communities affected by mosquito-borne diseases and deliver scalable solutions allowing businesses and communities to thrive, both now, and into the future.”

Kieran Walters | Director Global Functions & Strategy, World Mosquito Program

Project numbers

4 mobile labs completed Factory Acceptance Tests in Colombia

Up to 100 million Wolbachia mosquitoes to be produced weekly from the Brazil plant

86% projected reduction in dengue hospitalizations

77% projected reduction in dengue incidents

10 million people reached by successful Wolbachia mosquito deployment

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